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Dr. O'Bryan's Gluten World

Dr. O'Bryan's Gluten World

Read about gluten sensitivity and how it affects you. Access research information, media, Q & A and see where Dr. O'Bryan will be speaking next.

Introduction by Dr. O'Bryan

Welcome to

Dr. O'Bryan is an internationally recognized speaker specializing in Gluten Sensitivity & Celiac Disease.
He is the Sherlock Holmes for chronic disease & metabolic disorders. Newsletter Newsletter

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Dr. O'Bryan's Latest


If you missed our "Now That You Know, Where Do You Go?"

webinar you can still purchase the digital download.





The “Now That You Know, Where Do You Go?” FREE webinar

is a follow-up event to The Gluten Summit.

The webinar covered what actions to take based on your symptoms,

including specific tests and practitioners who can assist with your diagnosis.










The Dark Side of Wheat - A Critical Appraisal of the Role of Wheat in Human Disease

by Sayer Ji, founder of


Please click on the green tab "Gluten World"

to read the entire article.




FROM Dr. O'Bryan on Day 5 of The Gluten Summit:


Let's talk about GLUTEN-RELATED DISORDERS, DEPRESSION and SUICIDE - painful topics which touch so many families.


After my recent publication of a letter from a mother whose celiac son committed suicide and who now wonders if cross-reactivity to milk may have played a role in his ongoing depression, I received a message:


“Dear Dr. O'Bryan,

I am appalled that you used that letter from a mother whose son committed suicide. There was absolutely no good reason to use that letter to say that MAYBE there is a cross-reactivity to dairy. Depression is a very complex disease. So .... milk killed her son??! How irresponsible. Most people do not appreciate sensational anecdotes. Dear poor lady. I grieve for her son.”

I would like to share with you my response-


“Thank you for your comments. And on this issue I will respectfully disagree. This is exactly what the Gluten Summit is intended to do - to bring awareness for the many possible complications of having a gluten-related disorder. Even when it is an unpleasant conversation.

Who will speak up? Who will say "Our Drs need to know that a dairy sensitivity MAY be the trigger for a lack of full recovery on a gluten-free diet for some celiac patients"?
Who will say this? So that the unnecessary suffering, illness, and mortality which touches so many individuals and families is reduced.


Regarding celiac disease and issues with milk:

More than 70% of all celiac subjects were found to have a primary lactase deficiency

Up to 50% of celiac patients also have an immune reaction to cows milk protein. This can be a cross-reactive situation and the patient, on a gluten-free diet but eating dairy, may still have elevated antibodies to gluten, with all of the accompanying potential symptoms, ie depression

What is the connection between celiac disease and depression?

Depression is ranked as the most common neuropsychiatric disturbance in celiac disease

Additionally, quality of life is reduced on a gluten-free diet-'In celiac disease, affective disorders should be ascribed to difficulties in adjusting to the chronic nature of the disease rather than directly to the disease itself, thus giving an indication for preventive liaison psychiatric interventions.



Who will speak up about gluten-related disorders and depression? We cannot run away or bury our heads in the sand. Kudos to that mother for her courage in sharing her story. Together let's open up the conversation about the many diverse impacts of gluten-related disorders – with or without a gluten-free diet - so that perhaps another may not need to suffer unnecessarily.


Tom O'Bryan, DC, CCN, DACBN





FROM Dr. O'Bryan on Day 4 of The Gluten Summit:


Why did we call this event

“A Grain of Truth: The Gluten Summit”?

One of the reasons...

In 2010, only 28 (27%) of the 105 medical schools in the U.S. met the minimum 25 required (nutritional) hours set by the National Academy of Sciences; 6 years earlier, in 2004, 40 (38%) of 104 schools did so. [Read more.

From student….

“I am a medical student, finishing up this year, and I feel that I have learned more from your interviews in the last few days than I have in many of my medical school classes... SCARY!!! Thank you again for the opportunity to learn from so many incredible people, and for helping me be a better physician for my patients in the near future.” ~Tia

To healthcare professional…

“As a child and adult psychiatrist using IgG testing everyday I'm so pleased to now connect with this unforgettable library of remarkable experts. The best part: something for everyone, from the newbie, just not sure about what-is-gluten, to the next level of gluten-and-brain, to the advanced level of testing and scientific resources to provide applications that work in any office, anywhere in the world. Exemplary work by all, these presentations set new Gold Standards.” ~Dr. Parker in Virginia

… our educational system needs to know the grain of truth!


Tom O'Bryan, DC, CCN, DACBN




FROM Dr. O'Bryan on Day 3 of The Gluten Summit:


One of my favorite quotes from Day Two:

"I have a gluten free bakery that's part of a small cafe--I can't tell you how many people come in and say things like, "O, gluten-free is such a fad!" I wish we could blast these interviews and all this incredibly valuable information from a TV screen sixty feet high!" ~Cindy in Texas



Hey Everyone - When you purchase the $67 package (by November 18th) at The Gluten, you will receive digital files of all 29 interviews - to blast on any size TV screen you may have in your practice or business!





From Dr. O'Bryan on Day 2 of The Gluten Summit:


IMPORTANT: Can People With Celiac Disease Drink Gluten-Containing Beer?

Q: Dear Dr. O'Bryan, in his interview Dr. Marsh said it is ok for celiacs to drink English beer. Does that mean I can go ahead and order a beer?

A: All Right Folks, I have to intervene now. Dr. Marsh is truly the 'Godfather of Celiac Diagnosis' but he would be the first to tell you he is not an expert in WHICH foods work and do not work on a GFD. I have to urge caution before breaking a GFD with gluten-containing beer. If someone wants to do this, it's early in the week, I'll talk about this in detail at the end of this Summit, but I cannot have people thinking I am endorsing gluten-containing beer. The only way to do this would be to do a panel looking at multiple peptides of gluten, confirm that there are no elevated antibodies to any of the peptides of gluten (whether in wheat, rye or barley). If all are negative, then doing a beer challenge will tell you if it's ok for you.


Please CLICK HERE to read my paper on this topic of gluten challenges - 'Do I have to Re-introduce Gluten in Order to have an Accurate Gluten Sensitivity Test Done?'


Once again, NOT recommended to do, but if you are going to, this is the safest protocol. 

Take care of yourselves folks. 
Tom O'Bryan, DC, CCN, DACBN





Thank you all for the amazing comments during the first day of The Gluten Summit!  You make this effort of our entire Staff worthwhile.  At this point there are hundreds of comments - thank you again.



     Tom O'Bryan, Founder of



Following are my comments to just one of the posts we received on our Facebook page today during the first day of The Gluten Summit:

Is the gold standard test for celiac disease a DNA test? - Mari


First, "thank you" Mari for your words. However, there is a misconception that a DNA test is the 'gold standard'. This is a common misconception that earlier literature suggested and some Drs have continued to express. As technology improves, and more research is published, updates in our understanding occur. 

Studies are very clear that up to 1/3rd of the population of European descent carry the genes HLA-DQ2 and/or HLA-DQ8. But only 1% develop CD. This gene test is NOT the gold standard for diagnosis of CD. It IS a 'gold standard' for identifying that there is a risk for a Gluten-Related Disorder (GRD)

Some studies show up to 25% of celiacs do NOT have the genes HLA-DQ2 or DQ8 


And up to 50% of those with non-celiac gluten sensitivity (NCGS) DO have the genes HLA-DQ2 or DQ8. So it is no longer accurate to say the genes are the 'Gold Standard' for diagnosing CD. It IS accurate to say these genes are directly associated with a vulnerability to a Gluten Related Disorder (GSD)



Stay tuned for more from The Gluten Summit......


Dr. O'Bryan recently collaborated with Italian researchers and doctors who specialize in Menière Disease.  Their paper demonstrates the association of non-celiac gluten sensitivity (NCGS) in Menière Disease. This is the first paper that demonstrates the association of NCGS and Menière Disease.  Click here to read this important collaboration with F. DiBerardino, E. Filipponi, D. Alpini, T. O'Bryan, D. Soi and A. Cesarani.

The most basic Paleo Diet recommendation is the removal of gluten. But did you know that gluten sensitivity goes well beyond the digestive tract? Dr. O’Bryan reveals the latest research on how gluten consumption may lead to autoimmune disease, osteoporosis, and muscle pain without digestive symptoms.
Listen Here to the interview with Sean Croxton of Underground Wellness

The single most important risk factor for celiac disease is having a first-degree relative with already-defined celiac disease, particularly a sibling. A rate up to 20% or more has been noted.
World J Gastroenterol 2010 April 21; 16(15): 1828-1831

The prevalence of Celiac Disease has increased five-fold overall since 1974. This increase was not due to increased sensitivity of testing,but rather due to an increasing number of subjects that lost the immunological tolerance to gluten in their adulthood.   Ann Med. 2010 Oct;42(7):530-8

The incidence of Restless Leg Syndrome (RLS) in 85 consecutive patients with Celiac Disease was 35%.    Iron-deficient anemia was also present in 4 out of 10. Six months of a gluten-free diet improved RLS symptoms in 50%.   Dig Dis Sci. 2010 Jun;55(6):1667-73



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